In this interview, Matt speaks with Dr. Paul Williams about the SPRINT Trial of Intensive blood pressure control and how it is likely to change clinical practice. Tony and Stuart were absent for the interview, but don’t freak out. We added their take home points on the SPRINT trial to the outro segment.
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*SPRINT included: Patients over 50 years old with any of the following: eGFR 20-60 ml/min, symptomatic or asymptomatic CV disease, age 75 years old or greater, Framingham 10 year Risk above 15%
**SPRINT excluded: institutionalized adults, patients with diabetes, active malignancy, proteinuria, or prior stroke
The SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med 2015;373:2103-2116.
https://pubmed.ncbi.nlm.nih.gov/26551272/
ACCORD Study Group. Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med 2010;362:1575–1585. PMID: 20228401
http://www.ncbi.nlm.nih.gov/pubmed/20228401
HYVET Study group. Treatment of hypertension in patients 80 years of age or older. N Engl J Med. 2008;358:1887–98. PMID: 18378519 http://www.ncbi.nlm.nih.gov/pubmed/18378519
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