Get to know the non-Vitamin K oral anticoagulants, as The Curbsiders discuss these novel medications and other changes associated with the updated 2016 CHEST guidelines for anticoagulation.
SPARCtool – Atrial Fib Stroke Risk Tool
A great starting point for learning the NOACs
The new oral anticoagulants: Reasonable alternatives to warfarin. Cleve Clin J Med. 2015 Dec;82(12):847-54. doi: 10.3949/ccjm.82a.14052.
An indepth review article and summary of the new oral anticoagulants
Overview of the new oral anticoagulants: opportunities and challenges. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1056-65. doi: 10.1161/ATVBAHA.115.303397. Epub 2015 Mar 19.
Updated CHEST guidelines 2016
Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report. Chest. 2016;149(2):315-352. doi:10.1016/j.chest.2015.11.026
The original HAS-BLED article
A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010 Nov;138(5):1093-100. doi: 10.1378/chest.10-0134. Epub 2010 Mar 18.
A few articles that tell us bleeding related to falls are overestimated by physicians
Stroke and major bleeding risk in elderly patients aged ≥75 years with atrial fibrillation: the Loire Valley atrial fibrillation project. Stroke. 2015 Jan;46(1):143-50. doi: 10.1161/STROKEAHA.114.007199. Epub 2014 Nov 25.
Risk of falls and major bleeds in patients on oral anticoagulation therapy. Am J Med. 2012 Aug;125(8):773-8. doi: 10.1016/j.amjmed.2012.01.033.
Choosing antithrombotic therapy for elderly patients with atrial fibrillation who are at risk for falls. Arch Intern Med. 1999 Apr 12;159(7):677-85.
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A few things on this one. Overall great show. I learn something every time. But, please don't record in the bathroom anymore. The acoustics really are lousy. Second, a substantial PE is below the segmental arteries. Main PA>>segmental PA. Just like trachea>>mainstem bronchi>>segmental bronchi.
Please include a download link to this podcast